Browsing by Author "Cainelli, F."
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Cainelli, F.; Vallone, A.; Tanko, M. N.; Vento, S. (Elsevier, http://www.elsevier.com, NaN, 2010)[more][less]
Abstract: Lymphadenopathy was identified as an essential feature of AIDS soon after its appearance and before the identification of HIV as its cause.¹ However, lymphadenopathy has not subsequently received much attention. Recently, two studies have allowed lymph nodes to regain centre stage. URI: http://hdl.handle.net/10311/582 Files in this item: 1
Lymph nodes and pathogenesis.pdf (355.1Kb) -
Cainelli, F.; Vallone, A. (Dove Medical Press Ltd. http://www.dovepress.com/biologics-targets--therapy-journal, NaN, 2009)[more][less]
Abstract: Kaposi’s sarcoma is a vascular tumor linked to the presence of Kaposi’s sarcoma-associated herpesvirus (human herpesvirus-8) and the incidence of which has increased considerably the world over after the onset of the human immunodeficiency virus (HIV) pandemic. Antiretroviral therapy combined with cytotoxic agents has been established as the treatment of choice in the past 10 years. Among chemotherapeutic agents, pegylated liposomal doxorubicin has become the preferred one for patients with HIV-associated Kaposi’s sarcoma in Western countries. The drug in this formulation localizes better to the tumor and has higher efficacy. Skin toxicity, mucositis, and leukopenia/neutropenia are the main side effects. Hepatotoxicity and mild cardiotoxicity are observed less frequently. Pegylated liposomal doxorubicin impacts favorably on quality of life. Although cost effective in Western countries, the drug is less so in developing countries. URI: http://hdl.handle.net/10311/419 Files in this item: 1
Safety and efficacy.pdf (737.4Kb)
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