Three new flavonoids-5,7,4'-trihydroxy-6-[1-hydroxy-2-methylbuten-2-yl]isoflavone (isogancaonin C), 7,2'-dihydroxy-4'-methoxyisoflav-
3-ene (bolusanthin III), 6,6'-dihydroxy-4'-methoxy-2-arylbenzofuran (bolusanthin IV), in addition to eight known flavonoids;
derrone, medicarpan, genistein, wighteone, lupiwighteone, gancaonin C, 7-hydroxy-4'-methoxyisoflavone and 7,3'-dihydroxy-4'-
methoxyisoflavone were isolated from the root wood of Bolusanthus speciosus.The compounds showed strong antimicrobial
activity against Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Candida mycoderma.The isolated compounds also
showed moderate to strong radical scavenging properties against DPPH radical with the highest activities shown by the 2-arylbenzofuran,
the isoflav-3-ene and 7,3'-dihydroxy-4'-methoxyisoflavone in decreasing order.