Browsing Chemistry by Title
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Mbaveng, A.; Ngameni, B.; Kuete, V.; Simo, I.K.; Ambassa, P.; Roy, R.; Bezabili, M.; Etoa, F.X.; Ngadjui, B.; Abegaz, B.; Meyer, J.J.M.; Lall, N.; Beng, V.P. (Elsevier Ireland Ltd. http://www.elsevier.com/wps/find/journaldescription.cws_home/506035/description#description, NaN, 2008)[more][less]
Abstract: The aim of this study was to evaluate the antimicrobial activity of the crude extract of the twigs of Dorstenia barteri (DBT) as well as that of four of the five flavonoids isolated from this extract. Gram-positive bacteria (six species), Gram-negative bacteria (12 species) and fungi (four species) were used. The agar disc diffusion test was used to determine the sensitivity of the tested samples while the well micro-dilution was used to determine the minimal inhibition concentrations (MIC) and the minimal microbicidal concentration (MMC) of the active samples. The results of the disc diffusion assay showed that DBT, isobavachalcone (1), and kanzonol C (4) prevented the growth of all the 22 tested microbial species. Other compounds showed selective activity. The inhibitory activity of the most active compounds namely compounds 1 and 4 was noted on 86.4% of the tested microorganisms and that of 4-hydroxylonchocarpin (3) was observed on 72.7%. This lowest MIC value of 19.06 g/ml was observed with the crude extract on seven microorganisms namely Citrobacter freundii, Enterobacter aerogens, Proteus mirabilis, Proteus vulgaris, Bacillus megaterium, Bacillus stearothermophilus and Candida albicans. For the tested compounds, the lowest MIC value of 0.3 g/ml (on six of the 22 organisms tested) was obtained only with compound 1, which appeared as the most active compound. This lowest MIC value (0.3 g/ml) is about 4-fold lower than that of the RA, indicating the powerful and very interesting antimicrobial potential of isobavachalcone (1). The antimicrobial activities of DBT, as well as that of compounds 1, 3, 4, amentoflavone (5) are being reported for the first time. The overall results provide promising baseline information for the potential use of the crude extracts from DBT as well as some of the isolated compounds in the treatment of bacterial and fungal infections. URI: http://hdl.handle.net/10311/234 Files in this item: 2
Antimicrobial activity of the crude.pdf (2.258Mb)license.txt (1.998Kb) -
Kuete, V.; Ngameni, B.; Tsafack, A.M.; Ambassa, P.; Simo, I.K.; Bezabih, M.; Etoa, F.; Ngadjui, BT; Abegaz, B.M.; Beng, V.P. (Pharmacologyonline. http://www.pharmacologyonline.org/, NaN, 2007)[more][less]
Abstract: The crude extract from the twigs of Dorstenia elliptica (DET) as well one of the five compounds isolated from this extract namely O-[3-(2, 2-dimethyl-3-oxo-2H-furan-5-yl)-3- hydroxybutyl]bergaptol (5) were tested for their antimicrobial activity against bacteria and fungi. The Agar disc diffusion test was used to determine the sensitivity of the tested samples while the well micro-dilution was used to determine the minimal inhibition concentrations (MIC) and the minimal microbicidal concentration (MMC) of the active samples. The results of the disc diffusion assay showed that DET prevented the growth of all the 22 tested microbial species while the two tested compounds showed selective activity. At the tested MIC interval ranged from 1.22 to 156.25 μg/ml for the crude extracts and 0.08 to 39.06 μg/ml for the compounds, the activity of DET was noted on 20 of the 22 microbial species. The antimicrobial activities of DET as well as that compound 5 are being reported for the first time. The overall results provide promising baseline information for the potential use of the crude extract in the treatment of bacterial and fungal infections. URI: http://hdl.handle.net/10311/287 Files in this item: 1
ANTIMICROBIAL ACTIVITY OF THE.pdf (4.398Mb) -
Kuete, V.; Metuno, R.; Ngameni, B.; Ngandeu, F.; Bezabih, M.; Etoa, F-X.; Ngadjui, B.; Abegaz, B.; Beng, V. (Elsevier Ltd. www.elsevier.com/locate/sajb, NaN, 2007)[more][less]
Abstract: The crude methanolic extracts from Treculia africana and Treculia acuminata, three compounds isolated from T. africana and identified as, Phyllocoumarin (1), Catechin (2) and 6, 9-dihydroxy-megastigmane-3-one (3), four compounds namely 2, 3, 2,3-dihydroxypropyl-heptadecanoate (4), and Ferulic acid (5) isolated from T. acuminata were tested for their antimicrobial activity against Gram-positive bacteria (six species), Gramnegative bacteria (12 species) and three Candida species. The micro-dilution method for the determination of the minimal inhibition concentration (MIC) and the Minimal microbicidal concentration (MMC) was used. The MIC values obtained with the crude extracts varied from 78 to 156 à ¼g/ ml against 12 (57.14%) and 20 (95.24%) of the 21 tested microorganisms respectively for T. acuminata and T. africana. Apart from compound 2 that prevented the growth of all the tested microorganisms, other bioactive compounds showed selective activity. The obtained results provide promising baseline information for the potential use of these crude extracts as well as some of the isolated compounds in the treatment of bacterial and fungal infections. URI: http://hdl.handle.net/10311/245 Files in this item: 2
license.txt (1.998Kb) -
Kuete, V.; Metuno, R.; Ngameni, B.; Tsafack, A.M.; Ngandeu, F.; Fotso, G.W.; Bezabih, M.; Etoa, F.; Ngadjui, B.T.; Abegaz, B.M.; Penlap, B.V. (Elsevier Ireland Ltd. www.elsevier.com/locate/jethpharm, NaN, 2007)[more][less]
Abstract: The crude extract from Treculia obovoidea was subjected to purification by repeated chromatography. Eight compounds were isolated from Treculia obovoidea and identified as Psoralen (1), Bergapten (2), 7-methoxycoumarin (3), 7-hydroxycoumarin (4), 4,2 ,4 -trihydroxychalcone (5), 4,2 ,4 -trihydroxy-3-prenylchalcone (6), 3-hydroxy-4-methoxybenzoic acid (7) and O-[3-(2,2-dimethyl-3-oxo-2H-furan-5-yl) butyl] bergaptol (8). These compounds together with the extract were tested for their antimicrobial activity against Gram-positive bacteria (six species), Gram-negative bacteria (12 species) and three Candida species using micro-dilution methods for the determination of the minimal inhibition concentration (MIC) and the minimal microbicidal concentration (MMC). The MIC values obtained with the crude extracts varied from 78.12 to 156.25 g/ml against 17 (80.95%) of the 21 tested microorganisms. All the isolated compounds showed selective activity. The antimicrobial activity of this plant as well as that of compounds 6 and 8 is being reported for the first time. The obtained results provide promising baseline information for the potential use of these crude extract as well as some of the isolated compounds in the treatment of bacterial and fungal infections. URI: http://hdl.handle.net/10311/288 Files in this item: 1
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Erasto, P.; Bojase-Moleta, G.; Majinda, R.T. (Elsevier Ltd. www.elsevier.com/locate/phytochem, NaN, 2004)[more][less]
Abstract: Three new flavonoids-5,7,4'-trihydroxy-6-[1-hydroxy-2-methylbuten-2-yl]isoflavone (isogancaonin C), 7,2'-dihydroxy-4'-methoxyisoflav- 3-ene (bolusanthin III), 6,6'-dihydroxy-4'-methoxy-2-arylbenzofuran (bolusanthin IV), in addition to eight known flavonoids; derrone, medicarpan, genistein, wighteone, lupiwighteone, gancaonin C, 7-hydroxy-4'-methoxyisoflavone and 7,3'-dihydroxy-4'- methoxyisoflavone were isolated from the root wood of Bolusanthus speciosus.The compounds showed strong antimicrobial activity against Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Candida mycoderma.The isolated compounds also showed moderate to strong radical scavenging properties against DPPH radical with the highest activities shown by the 2-arylbenzofuran, the isoflav-3-ene and 7,3'-dihydroxy-4'-methoxyisoflavone in decreasing order. URI: http://hdl.handle.net/10311/299 Files in this item: 1
Antimicrobial and antioxidant.pdf (3.228Mb) -
Chacha, M.; Bojase-Moleta, G.; Majinda, R.R.T. (Elsevier Ltd; http://www.elsevier.com/wps/find/journaldescription.cws_home/273/description, November 20, 2004)[more][less]
Abstract: From the stem wood of Erythrina latissima, two isoflavones and a flavanone were isolated and characterized as 7,3'-dihydroxy-4'-methoxy-5'-(y,y-dimethylallyl)isoflavone (erylatissin A), 7,3'-dihydroxy-6".6"-dimethyl-4".5"-dehydropyrano [2",3":4'.5']isoflavone (erylatissin B), (-)-7,3'-dihydroxy-4'-methoxy-5'-(y,y-dimethylallyl)flavanone (erylatissin C), respectively, in addition to 10 known flavonoids. Structures of these compounds were determined on the basis of their spectroscopic data. These compounds showed antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Candida mycoderma. The isolated compounds also exhibited weak radical scavenging properties towards DPPH radical. URI: http://hdl.handle.net/10311/216 Files in this item: 2
license.txt (1.998Kb) -
Omisore, N.; Adewunmi, C.; Iwalewa, E.; Ngadjui, B.; Watchueng, J.; Abegaz, B.; Ojewole, J. (Elsevier Ltd. www.elsevier.com/locate/jethpharm, NaN, 2004)[more][less]
Abstract: The present studywas undertaken to investigate the antinociceptive and anti-inflammatory activities of the leaf and twig extracts of Dorstenia barteri (Moraceae) in mice. Both the leaf and twig extracts of Dorstenia barteri at 50, 100 and 200 mg/kg showed significant (P < 0.05-0.01) antinociceptive activities in chemical-, mechanical- and thermal-induced pain test models. Intraperitoneal administration of the plant extracts at 50, 100 and 200 mg/kg significantly (P < 0.05-0.01) inhibited carrageenin-induced acute inflammation in oedema paw weight, pulmonary oedema and number of pleural leucocytes in a dose-dependent way. The twig extract was found to be more active than the leaf extract in all the experimental models used. The inhibitory effects of the plant extracts were comparable to those of the reference drugs acetylsalicyclic acid (ASA) and phenylbutazone (PBZ) at 100 mg/kg i.p. The significant reduction in acetic acid-induced abdominal contractions, the decrease in oedema paw weight as well as in the number of leucocytes in the pleural cavity exudates, and the significant increase in the reaction time and pain threshold of mice observed in this study suggest that Dorstenia barteri extracts possess both anti-inflammatory and antinociceptive activities. The present study, therefore, lend pharmacological support to the folkloric uses of Dorstenia barteri extracts in the treatment, control and/or management of arthritis, rheumatism, gout, headache and other forms of body pains in some parts of Africa. URI: http://hdl.handle.net/10311/256 Files in this item: 2
license.txt (1.998Kb) -
Antioxidant activity of prenylated flavonoids from the West African medicinal plant Dorstenia manniiDufall, K.; Ngadjui, B.; Simeon, K.; Abegaz, B.; Croft, K. (Elsevier Science Ireland Ltd. www.elsevier.com/locate/jethpharm, NaN, 2003)[more][less]
Abstract: The antioxidant activities of three prenylated flavonoids from Dorstenia mannii (6,8-diprenyleriodictyol, dorsmanin C and dorsmanin F) were compared to the common, non-prenylated flavonoid, quercetin. The prenylated flavonoids were found to be potent scavengers of the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH), and are more potent than butylated hydroxy toluene (BHT), a common antioxidant used as a food additive. The prenylated flavonoids also inhibited Cu2+-mediated oxidation of human low density lipoprotein (LDL). Dose-response studies indicated that the prenylated flavonoids were effective inhibitors of lipoprotein oxidation with IC50 values <1 M and had similar inhibitory potency compared to quercetin, but was not directly related to Cu binding. Unlike quercetin, they did not show any pro-oxidant activity at high doses in the Cu2+-mediated lipoprotein oxidation system. The medicinal action of Dorstenia mannii may be related to the high concentration of potent antioxidant prenylated flavonoids in this species. URI: http://hdl.handle.net/10311/261 Files in this item: 2
license.txt (1.998Kb) -
Omisore, N.O.A.; Adewunmi, C.O.; Iwalewa, E.O.; Ngadjui, B.T.; Adenowo, T.K.; Abegaz, B.M.; Ojewole, J.A.; Watchueng, J. (Brazilian Journal of Medical and Biological Research. http://www.scielo.br/scielo.php?pid=0100-879X&script=sci_serial, NaN, 2005)[more][less]
Abstract: Dorstenia barteri and D. convexa extracts and some isolated components of the former were investigated for effectiveness against Trichomonas gallinarum and compared with quercetin and quercitrin. The antioxidant activity of the extracts/compounds was also determined. The minimum lethal concentrations (MLCs) for the extract of D. barteri leaves and twigs at 24 h were found to be 15.625 and 15.625 μg/ml, respectively. However, the MLCs of the leaf and twig extract of D. convexa were 125 and 437.5 μg/ml, respectively. The prenylated and geranylated chalcones were as active as the prenylated flavones, 6- prenylapigenin and the diprenylated derivative 6,8-diprenyleridictyol. The order of the antitrichomonal activity of the compounds at 24 h was: quercetin (0.121 μg/ml) > quercitrin (0.244 μg/ml) ≥ bartericin B (0.244 μg/ml) > bartericin A (0.73 μg/ml) > stigmasterol (0.98 μg/ml) > 6,8-diprenyleridictyol = isobavachalcone = dorsmanin F (31.25 μg/ ml). D. barteri extracts, quercitrin, and bartericin A, and the prenylated flavonoids had potent antioxidant properties. The twig extract of D. barteri was more potent than the leaf extract. Moderate (EC50 >50 μg/ ml) and high (EC50 <50 μg/ml) antioxidant activities were detected in the leaf and twig extracts of D. barteri and the prenylated flavonoids. Prenylated flavonoids and the isolated compounds with antioxidant properties described here may account for the anti-inflammatory action of these extracts. The antitrichomonal and antioxidant activities shown by the extracts and compounds in this study are consistent with the ethnomedicinal and local use of the Dorstenia species studied. URI: http://hdl.handle.net/10311/284 Files in this item: 1
Antitrichomonal and antioxidant.pdf (2.508Mb) -
Masesane, I.B.; Yeboah, S.O.; Liebscher, J.; Mugge, C.; Abegaz, B.M. (Elsevier Science Ltd, http://www.elsevier.com/locate/phytochem, NaN, 2000)[more][less]
Abstract: The twigs of Rhus pyroides yielded a novel bichalcone 2',40,21-trihydroxy-4',41-dimethoxy-4-O-51-bichalcone. It was identified on the basis of spectroscopic data including 1D and 2D NMR spectroscopy. The name rhuschalcone-1 is proposed. URI: http://hdl.handle.net/10311/1028 Files in this item: 1
Masesane_P_2000.pdf (321.5Kb) -
Keter, F.K.; Ojwach, S.O.; Oyetunji, O.A.; Guzei, I.A.; Darkwa, J. (Elsevier Science Ltd, www.elsevier.com/locate/ica, NaN, 2009)[more][less]
Abstract: A series of pyrazolyl palladium(II), platinum(II) and gold(III) complexes, [PdCl2(3,5-R2bpza)] {R = H (1), R = Me (2), bpza = bis-pyrazolyl acetic acid}, [PtCl2(3,5-R2bpza)] {R = H (3a), R = Me (4)}, [AuCl2(3,5- R2bpza)]Cl {R = H (5a), R = Me (6a)} and [PdCl2(3,5-R2bpzate)] {R = Me (7)} have been synthesised and structurally characterised. Single crystal X-ray crystallography showed that the pyrazolyl ligands exhibit N^N-coordination with the metals. Anticancer activities of six complexes 1–6a were investigated against CHO cells and were found to have low activities. Substitution reactions of selected complexes 1, 2, 3a and 5a with L-cysteine show that the low anticancer activities compounds and that the rate of substitution with sulfur-containing compounds is not the cause of the low anticancer activities. URI: http://hdl.handle.net/10311/1032 Files in this item: 1
Keter_ICA_2009.pdf (1.240Mb) -
Jain, P.K.; Lungu, E.M.; Prakash, J. (Elsevier Science Ltd. www.elsevier.com/locate/renene, NaN, 2003)[more][less]
Abstract: The Republic of Botswana is one of the sunniest countries in Southern Africa. It has very little cloud cover, insufficient rainfall, very low humidity, and very low wind speed throughout the year for most parts of the country. The daily extremum temperatures appear to be very much related to solar irradiation which in turn depends on sunshine duration. In Botswana, solar irradiation on a horizontal surface is measured only at Sebele, but sunshine duration and extremum temperatures are measured at several locations throughout the country. This paper presents bivariate models that relate solar irradiation to sunshine duration, and solar irradiation to extremum temperatures for Sebele, Botswana. Autocorrelation analysis revealed that the solar irradiation series is stationary for d=2 and D=0, sunshine duration series is stationary for d=0 and D=0, while the extremum temperatures series are stationary for either d=0 and D=N where N=1, 2, . . . or d=1 and D=1. It is found that there is a lag of three months between the peaks of the differenced series of fractional sunshine duration and fractional solar irradiation. On the other hand it is found that there is at most a lag of one month between the peaks of the differenced series of maximum temperature and solar irradiation, and that there is no lag between the peaks of the differenced series of minimum temperature and solar irradiation. Analysis of the noise component revealed that the bivariate processes under consideration behaved either as a purely seasonal MA processes of order (0,1,1) or as ARIMA processes of order (0, 1, 1)x (0, 1, 1)12 or as a purely nonseasonal, autoregressive process of order 2. We claim that the relationships found for Sebele can be applied to estimate solar irradiation at other locations with climatic conditions similar to Botswana. URI: http://hdl.handle.net/10311/177 Files in this item: 2
jain_RE_2003.pdf (1.288Mb)license.txt (1.998Kb) -
Abegaz, B.M.; Ngadjui, B.T.; Dongo, E.; Ngameni, B.; Nindi, M.N.; Bezabih, M. (Elsevier Science Ltd. www.elsevier.com/locate/phytochem, NaN, 2002)[more][less]
Abstract: The twigs of Dorstenia prorepens furnished the digeranylated chalcone, 5,30-(3,7-dimethyl-2,6-octadienyl)-3,4, 20,40-tetrahydroxychalcone while Dorstenia zenkeri yielded the 30,40-(3-hydroxy-2,2-dimethyldihydropyrano)-4,20-dihydroxychalcone and a bichalcone. 4-Hydroxylonchocarpin was found in both plants. D. prorepens also yielded the known compounds: psoralen, bergapten, b-sitosterol and its D-glucopyranosyl derivative. D. zenkeri yielded p-hydroxybenzaldehyde, dorsmanin A, 4,20,40-trihydroxychalcone and 4,20,40-trihydroxy-30-prenylchalcone. Structures of the new compounds were established by UV, IR, MS and 2-D NMR analysis. URI: http://hdl.handle.net/10311/254 Files in this item: 2
Chalcones and other constituents.pdf (3.760Mb)license.txt (1.998Kb) -
Mabaleha, M.B.; Yeboah, S.O. (AOCS Press., NaN, 2004)[more][less]
Abstract: Seed oils from six legume cultivars of Phaseolus vulgaris, grown in the Kingdom of Lesotho, were extracted and their physicochemical properties and FA compositions were determined in order to compare their dietary lipids with those in P. vulgaris cultivars grown in other parts of the world. The oil content of the beans was very low, ranging from 1.5 to 2.0% (w/w). The acid values ranged from 11.0 to 19.2 mg KOH/g, whereas a combination of the PV and the p-anisidine values in Holm’s equation gave oxidation values that ranged from 11.0 to 15.0. Thus, considerable enzymatic hydrolysis and oxidation had taken place in the beans during storage. Iodine values ranged from 80.5 to 92.3 (Wijs method), indicating moderate unsaturation in the oils. However, capillary GC analysis, supported by proton NMR analysis of the FAME, gave a total unsaturation range from 79.67 to 84.24%. The dominant FA were α-linolenic acid (36.47–48.81%) and linoleic acid (20.96–36.10%), with appreciable amounts of palmitic acid (14.33–18.23%). This FA composition pattern is quite similar to the FA distribution reported for low oil-bearing legume seeds. Thus, notwithstanding the different climatic and soil conditions, the general properties of lipids in the southern African legume cultivars were quite similar to those of lipids in P. vulgaris cultivars grown in other parts of the world. The high content of α-linolenic acid in the cultivars of P. vulgaris could very likely play a beneficial role in reducing the risk of coronary heart disease among the large populations consuming them in the southern African region. URI: http://hdl.handle.net/10311/303 Files in this item: 1
Characterization and compositional.pdf (3.533Mb) -
Metuno, R.; Ngandeu, F.; Tchinda, A.T.; Ngameni, B.; Kapche, G.D.W.F.; Djemgou, P.C.; Ngadjui, B.T.; Bezabih, M.; Abegaz, B.M. (Elsevier Ltd. www.elsevier.com/locate/biochemsyseco, NaN, 2007)[more][less]
Abstract: Three species of the genus Treculia namely, Treculia acuminata Baill., Treculia africana Decne ex. Treà ´cul and Treculia obovoidea N.E.Br. grow in the humid rain forest of southwest Cameroon. They are also widely distributed in tropical Africa. T. africana is commonly known as African bread fruit. These three species are commonly used in folk medicine against skin diseases and dental allergies (Berg et al., 1985). The twigs, stem and wood of T. acuminata and the leaves of T. africana, whose chemical constituents are reported herein, were collected from Kumba, Cameroon, in August 2004, and identified by Mr Victor Nana of the National Herbarium in Yaounde, Cameroon where voucher specimens (N 2921/Srf/CAM and 29053/SRF/Cam, respectively) are deposited. URI: http://hdl.handle.net/10311/291 Files in this item: 1
Chemical constituents of Treculia.pdf (2.209Mb) -
Ahmad, J.; Bothata-Nareetsile, F.; Becker, C.A.L. (NRC Research Press, http://www.nrcresearchpress.com/loi/cjc, NaN, 2003)[more][less]
Abstract: Nine pairs of corresponding [CoI(CNR)3(PR3 ′ )2]X, [CoII(CNR)3(PR3 ′ )2]X2 complexes — where X = ClO4, BF4; CNR = CNCMe3, CNCHMe2, CNC6H11, CNCH2Ph; PR3′ = PPh3, P(C6H4Me-p)3, P(C6H4OMe-p)3 — have been studied using cyclic voltammetry in CH3CN solutions. All cycles are reversible, and E1/2 for the Co(I) complexes, initially oxidized, are within experimental error identical to E1/2 values for the corresponding Co(II) complexes, initially reduced. E1/2 values are strongly dependent on the triarylphosphine ligand, decreasing in the order PPh3 > > P(C6H4Me-p)3 > P(C6H4OMe-p)3, and weakly dependent on the alkylisocyanide ligand, decreasing in the order CNCH2Ph > CNCMe3 > CNC6H11 ≥ CNCHMe2. Solution ν(-N C) IR patterns reveal that the [CoI(CNR)3(PR3′)2]X complexes do not have regular trigonal bipyramidal coordination, their structure being determined by the particular CNR ligand, while the [CoII(CNR)3(PR3′)2]X2 complexes, specifically in CF3CH2OH, appear to have regular trigonal bipyramidal coordination. Description: Signs on the abstract may be different to the original document URI: http://hdl.handle.net/10311/1034 Files in this item: 1
Ahmad_CJC_2003.pdf (782.1Kb) -
Daka, P.S.; Obuseng, V.C.; Torto, N.; Huntsman-Mapila, P. (Water SA Pretoria; Water Research Commission; http://www.wrc.org.za/, October NaN, 2006)[more][less]
Abstract: Deltamethrin concentrations were determined in 35 sediment samples collected from three different habitats: channel, lagoon and pool sites from Xakanaxa in the Okavango Delta, NW Botswana. The samples were Soxhlet-extracted in acetone to extract deltamethrin residues and subsequently cleaned-up with silica gel 60. The final determination was carried out with a gas chromatograph equipped with an electron capture detector (GC-ECD). The sample work-up and determination gave deltamethrin recoveries of 54 to 97%, and detection limits of 0.004 mg/kg dw. The concentration of deltamethrin residues in the sediment samples collected from the three sprayed areas in the Okavango delta ranged between 0.013 and 0.291 mg/kg dw, with the highest concentrations observed in samples obtained from the pool sites. Analysis of samples for organic matter content showed percentage total organic carbon (% TOC) ranging between 0.19% and 8.21%, with samples collected from the pool having the highest total organic carbon. The concentrations of deltamethrin residues and the % TOC in sediment samples showed a similar trend with the highest levels recorded in the pool samples. These data confirmed that a simple method based on GC-ECD, after Soxhlet extraction, was robust enough to enable quantification of deltamethrin in the sediments, because comparable results were obtained with a more sophisticated system consisting of a GC coupled to a mass spectrometer with a time of flight (TOF) analyser. URI: http://hdl.handle.net/10311/140 Files in this item: 2
dakaetal.pdf (463.1Kb)license.txt (1.998Kb) -
Ngadjui, B.; Dongo, E.; Abegaz, B.; Fotso, S.; Tamboue, H. (Elsevier Science Ltd. www.elsevier.com/locate/phytochem, NaN, 2002)[more][less]
Abstract: Three prenylated flavonoids, dinklagins A, B and C identified, respectively, as ( )-6-(3,3-dimethylallyl)-7-hydroxy-6000, 6000-dimethylchromeno-( 40,30,2000,3000)-flavanone, (+)-5,40,500x-trihydroxy-600,600-dimethylchromano-(7,6,200,300)-flavone and (+)6-(2x-hydroxy- 3-methyl-3-butenyl)-5,7,40-trihydroxyflavone were isolated from the twigs of Dorstenia dinklagei together with the known 6-prenylapigenin, 4-hydroxylonchocarpin, stipulin and 5,40-dihydroxy-600,600-dimethylchromano-(7,6,200,300)-flavone. Their structures were determined on the basis of spectral data and by comparison with data reported in the literature and with authentic specimens for known compounds. URI: http://hdl.handle.net/10311/262 Files in this item: 2
license.txt (1.998Kb) -
Ngameni, B.; Ngadjui, B.; Folefoc, G.; Watchueng, J.; Abegaz, B. (Elsevier Ltd; www.elsevier.com/locate/phytochem, NaN, 2003)[more][less]
Abstract: The twigs of Dorstenia barteri var. subtriangularis yielded three diprenylated chalcones: ( )-3-(3,3-dimethylallyl)-50-(2-hydroxy-3- methylbut-3-enyl)-4,20,40-trihydroxychalcone, (+)-3-(3,3-dimethylallyl)-40,50-[2000-(1-hydroxy-1-methylethyl)-dihydrofurano]-4,20- dihydroxychalcone and 3,4-(600,600-dimethyldihydropyrano)-40,50-[2000,-(1-hydroxy-1-methylethyl)-dihydrofurano]-20-hydroxychalcone for which the names bartericins A, B and C, respectively, are proposed. Stipulin, b-sitosterol and its 3-b-D-glucopyranosyl derivative were also isolated. The structures of these secondary metabolites were determined on the basis of spectroscopic analysis, especially, NMR spectra in conjunction with 2D experiments, COSY, HMQC and HMBC. The structural relationship of bartericins B and C was further established by the chemical cyclization of one to the other. URI: http://hdl.handle.net/10311/258 Files in this item: 2
Diprenylated chalcones and other.pdf (3.479Mb)license.txt (1.998Kb) -
Ngadjui, B.T.; Abegaz, B.M.; Keumedjio, F.; Folefoc, G.N.; Kapchec, G.W.F. (Elsevier Science Ltd. www.elsevier.com/locate/phytochem, NaN, 2002)[more][less]
Abstract: Three clerodane diterpenoids, crotozambefurans A, B and C were isolated from the stem bark of Croton zambesicus together with the known clerodane crotocorylifuran and two trachylobanes: 7b-acetoxytrachyloban-18-oic acid and trachyloban-7b, 18-diol. Betulinol, lupeol, sitosterol and its 3b-glucopyranosyl derivative were also obtained. The structures of crotozambefurans A, B and C were determined, respectively, as: 15,16-epoxy-1,3,13(16),14-clerodatetraen-20,12-olide-18,19-dioic acid dimethylester, 15,16-epoxy- 1,3,13(16),14-clerodatetraen-18,19,20-trioic acid trimethylester and 15,16-epoxy-3,13(16),14-clerodatrien-19,1a:20,12-diolide-18-oic acid methylester, using spectroscopic analysis, especially, NMR spectra in conjunction with 2D experiments, COSY, HSQC, HMBC and TOCSY. URI: http://hdl.handle.net/10311/251 Files in this item: 2
Diterpenoids from the stem bark.pdf (2.493Mb)license.txt (1.998Kb)