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dc.contributor.author Erasto, P.
dc.contributor.author Bojase-Moleta, G.
dc.contributor.author Majinda, R.T.
dc.date.accessioned 2009-03-24T14:09:49Z
dc.date.available 2009-03-24T14:09:49Z
dc.date.issued 2004
dc.identifier.citation Erasto, P, et al (2004), Antimicrobial and antioxidant flavonoids from the root wood of Bolusanthus speciosus, Phytochemistry, vol. 65, pp. 875-880 en
dc.identifier.issn 0031-9422
dc.identifier.uri http://hdl.handle.net/10311/299
dc.description.abstract Three new flavonoids-5,7,4'-trihydroxy-6-[1-hydroxy-2-methylbuten-2-yl]isoflavone (isogancaonin C), 7,2'-dihydroxy-4'-methoxyisoflav- 3-ene (bolusanthin III), 6,6'-dihydroxy-4'-methoxy-2-arylbenzofuran (bolusanthin IV), in addition to eight known flavonoids; derrone, medicarpan, genistein, wighteone, lupiwighteone, gancaonin C, 7-hydroxy-4'-methoxyisoflavone and 7,3'-dihydroxy-4'- methoxyisoflavone were isolated from the root wood of Bolusanthus speciosus.The compounds showed strong antimicrobial activity against Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Candida mycoderma.The isolated compounds also showed moderate to strong radical scavenging properties against DPPH radical with the highest activities shown by the 2-arylbenzofuran, the isoflav-3-ene and 7,3'-dihydroxy-4'-methoxyisoflavone in decreasing order. en
dc.language.iso en en
dc.publisher Elsevier Ltd. www.elsevier.com/locate/phytochem en
dc.subject Bolusanthus speciosus en
dc.subject Fabaceae en
dc.subject Root wood en
dc.subject Flavonoids en
dc.subject 5,7,4'-Trihydroxy-6-[1-hydroxy-2-methylbuten-2-yl]isoflavone en
dc.subject 7,20-Dihydroxy-4'-methoxyisoflav-3-ene en
dc.subject 6,60-Dihydroxy-40-methoxy-2-arylbenzofuran en
dc.subject Antimicrobial en
dc.subject radical scavenging properties en
dc.title Antimicrobial and antioxidant flavonoids from the root wood of Bolusanthus speciosus en
dc.type Published Article en


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