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dc.contributor.author Mutanyatta, J.
dc.contributor.author Bezabih, M.
dc.contributor.author Abegaz, B.
dc.contributor.author Dreyer, M.
dc.contributor.author Brun, R.
dc.contributor.author Kocher, N.
dc.contributor.author Bringmann, G
dc.date.accessioned 2008-10-20T10:40:36Z
dc.date.available 2008-10-20T10:40:36Z
dc.date.issued 2005
dc.identifier.citation Mutanyatta, J. et al (2005) The first 60-O-sulfated phenylanthraquinones: isolation from Bulbine frutescens, structural elucidation, enantiomeric purity, and partial synthesis, Tetrahedron, vol. 61, pp. 8475 -8484 en
dc.identifier.issn 0040-4020
dc.identifier.uri http://hdl.handle.net/10311/246
dc.description.abstract From the roots of Bulbine frutescens, the first sulfated phenylanthraquinones were isolated, together with their known sulfate-free analogs. Their structures were elucidated by spectroscopic and chiroptical methods, by acid hydrolysis or by partial synthesis. The new compounds have the usual stereo-orientation at the biaryl axis (i.e., with the acetyl portion above the anthraquinone plane) except for sodium ent-knipholone 60-O-sulfate (and thus, also its hydrolysis product, ent-knipholone), which exhibit an opposite axial configuration. We also describe the first stereoanalysis of natural phenylanthraquinones, some of which were found to be not enantiomerically pure, some even nearracemic. We furthermore, report on the first X-ray structure analysis of a phenylanthraquinone, viz. 40-O-demethylknipholone. en
dc.language.iso en en
dc.publisher Elsevier Ltd.http://www.elsevier.com/wps/find/journaldescription.cws_home/942/description#description en
dc.subject LC-CD coupling en
dc.subject Bulbine frutescens en
dc.subject Sulfated phenylanthraquinones en
dc.subject Axial chirality en
dc.subject Enantiomeric resolution en
dc.subject Crystal structure. en
dc.title The first 60-O-sulfated phenylanthraquinones: isolation from Bulbine frutescens, structural elucidation, enantiomeric purity, and partial synthesis en
dc.type Article en


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