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dc.contributor.author Kuete, V.
dc.contributor.author Metuno, R.
dc.contributor.author Ngameni, B.
dc.contributor.author Ngandeu, F.
dc.contributor.author Bezabih, M.
dc.contributor.author Etoa, F-X.
dc.contributor.author Ngadjui, B.
dc.contributor.author Abegaz, B.
dc.contributor.author Beng, V.
dc.date.accessioned 2008-10-20T10:29:38Z
dc.date.available 2008-10-20T10:29:38Z
dc.date.issued 2007
dc.identifier.citation Kuete, V. et al (2007), Antimicrobial activity of the methanolic extracts and compounds from Treculia africana and Treculia acuminata (Moraceae), South African Journal of Botany, vol. 74, pp. 111-115 en
dc.identifier.issn 0254-6299
dc.identifier.uri http://hdl.handle.net/10311/245
dc.description.abstract The crude methanolic extracts from Treculia africana and Treculia acuminata, three compounds isolated from T. africana and identified as, Phyllocoumarin (1), Catechin (2) and 6, 9-dihydroxy-megastigmane-3-one (3), four compounds namely 2, 3, 2,3-dihydroxypropyl-heptadecanoate (4), and Ferulic acid (5) isolated from T. acuminata were tested for their antimicrobial activity against Gram-positive bacteria (six species), Gramnegative bacteria (12 species) and three Candida species. The micro-dilution method for the determination of the minimal inhibition concentration (MIC) and the Minimal microbicidal concentration (MMC) was used. The MIC values obtained with the crude extracts varied from 78 to 156 à ¼g/ ml against 12 (57.14%) and 20 (95.24%) of the 21 tested microorganisms respectively for T. acuminata and T. africana. Apart from compound 2 that prevented the growth of all the tested microorganisms, other bioactive compounds showed selective activity. The obtained results provide promising baseline information for the potential use of these crude extracts as well as some of the isolated compounds in the treatment of bacterial and fungal infections. en
dc.language.iso en en
dc.publisher Elsevier Ltd. www.elsevier.com/locate/sajb en
dc.subject Antimicrobial activity en
dc.subject Compounds en
dc.subject Moraceae en
dc.subject Treculia acuminata en
dc.subject Treculia africana en
dc.title Antimicrobial activity of the methanolic extracts and compounds from Treculia africana and Treculia acuminata (Moraceae) en
dc.type Article en


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