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dc.contributor.author Mazimba, O.
dc.contributor.author Majinda, R.R.T.
dc.contributor.author Motlhanka, D.
dc.date.accessioned 2013-08-07T09:30:30Z
dc.date.available 2013-08-07T09:30:30Z
dc.date.issued 2011-06
dc.identifier.citation Mazimba, O., Majinda, R.R.T. & Motlhanka, D. (2011) Antioxidant and antibacterial constituents from Morus nigra, African Journal of Pharmacy and Pharmacology, Vol. 5, No. 6, pp. 751-754 en_US
dc.identifier.issn 1996-0816
dc.identifier.uri http://hdl.handle.net/10311/1150
dc.description.abstract The objective of this study was to isolate and characterize the constituents of the local Morus nigra L. (Black mulberry), to compare its constituents with other studied Mulberries and to evaluate its antioxidative and anti-bacterial activities. The isolated compounds were identified by comparison of spectral data (UV, IR, MS and NMR) with literature values. The stem bark and wood of M. nigra yielded a stilbenoid oxyresveratrol 1, a 2-arylbenzofuran moracin M2, four isoprenylated flavonoids; cyclomorusin 3, morusin 4, kuwanon C5 and a derivative of kuwanon C6, two tritepenes; betulinic acid 7, -amyrin acetate 8 and a steroidal saponin -sitosterol-3-O- -D-glucoside 9. The phenolic isolates showed moderate DPPH radical scavenging activity (EC50 = 23-135 μgml-1) compared to ascorbic acid (EC50 = 41 μgml-1) after 30 min. Compounds 1, 2 and 4 to 6 showed activities against Staphylococcus aureus, Bacillus subtilis, Micrococus flavus, Streptococcus faecalis, Salmonella abony, Pseudomonas aeruginosa. en_US
dc.language.iso en en_US
dc.publisher Academic Journals, http://www.academicjournals.org/ajpp en_US
dc.subject Morus nigra en_US
dc.subject Antioxidant en_US
dc.subject Antibacterial en_US
dc.subject Oxyresveratrol en_US
dc.subject Isoprenylated flavonoids en_US
dc.title Antioxidant and antibacterial constituents from Morus nigra en_US
dc.type Published Article en_US
dc.link http://www.academicjournals.org/ajpp/PDF/pdf2011/June/Mazimba%20et%20al.pdf en_US


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