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dc.contributor.author Mazimba, O.
dc.contributor.author Masesane, I.B.
dc.contributor.author Majinda, R.R.
dc.date.accessioned 2012-08-08T07:51:35Z
dc.date.available 2012-08-08T07:51:35Z
dc.date.issued 2011
dc.identifier.citation Mazimba, O. et al (2011) An efficient synthesis of flavans from salicylaldehyde and acetophenone derivatives, Tetrahedron Letters, Vol. 52, No. 50, pp. 6716–6718 en_US
dc.identifier.issn 0040-4039
dc.identifier.uri http://hdl.handle.net/10311/1027
dc.description.abstract An efficient total synthesis of flavans from the reactions of salicylaldehyde and acetophenone derivatives is reported. The synthesis involves preparation of chalcones through an aldol reaction followed by reduction of both the double bond and the ketone using NaBH4 and an acetic acid mediated cyclization. Methoxy groups on the aromatic rings did not affect significantly the yields of the procedure. en_US
dc.language.iso en en_US
dc.publisher Elsevier Science Ltd, http://www.elsevier.com/locate/tetlet en_US
dc.subject Flavan en_US
dc.subject Acetophenone en_US
dc.subject Salicylaldehyde en_US
dc.subject Aldol condensation en_US
dc.subject Reduction en_US
dc.title An efficient synthesis of flavans from salicylaldehyde and acetophenone derivatives en_US
dc.type Published Article en_US
dc.link http://ac.els-cdn.com/S0040403911017023/1-s2.0-S0040403911017023-main.pdf?_tid=96c1b321c39be9004114565db90e546b&acdnat=1343895392_4106dd1da3300866fe3722c70fad6992 en_US


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